MASON ~ Y-DNA ~ PROJECT

Member

Kit 29978, James Mason (b. 1752), Joseph Redden Mason (b. abt 1880), Haplogroup R1b1 P25+

Oldest Known Ancestor

We want to prove/disprove a connection to John Mason² (b. 1662), the first Mason in Hyde Co. North Carolina.
James Mason⁵ (b. 1752) and wife Charity Swindell Mason, earliest known ancestors.
Generations:
1. William Mason (b. 1632 d. 1702) can't prove this connection
2. John Mason [estimated 1662] immigrant to Hyde county North Carolina, can't prove this connection
3. Thomas Mason [estimated 1698] can't prove this relationship
4. John Mason [estimated 1732] can't prove this relationship
5. James Mason⁵ (b. 1752) & Charity Swindell Mason, earliest known ancestors
6. Thomas Mason (b. 1780) and John Mason (b. 1778) John and Thomas were brothers - John's daughter married Dorset (son of Thomas).
7. Dorset Mason (b. 1808)
8. Jesse Simeon Mason (b. 1836)
9. Joseph Redden Mason⁹ (b. 1880)
10. (living) Mason (b. 1914)
11. (living) Mason
12. (living) Mason

Notes:

"The case of the unreliable SNP: Recurrent back-mutation of Y-chromosomal marker P25 through gene conversion" by Susan M. Adams, Turi E. King, Elena Bosch** and Mark A. Jobling, Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK. Received 9 May 2005; revised 7 June 2005; accepted 9 June 2005. Available online 18 July 2005.

Abstract:

The Y-chromosomal binary marker P25 is a paralogous sequence variant, rather than a SNP: three copies of the P25 sequence lie within the giant palindromic repeats on Yq, and one copy has undergone a C to A transversion to define haplogroup R1b (designated C/C/A). Since gene conversion is known to be active in the palindromic repeats, we reasoned that P25 might be liable to back-mutation by gene conversion, yielding the ancestral state C/C/C. Through analysis of a set of binary markers in Y-chromosomes in two large samples from Great Britain and the Iberian Peninsula we show that such conversion events have occurred at least twice, and provide preliminary evidence that the reverse conversion event (yielding C/A/A) has also occurred. Because of its inherent instability, we suggest that P25 be used with caution in forensic studies, and perhaps replaced with the more reliable binary marker M269.
Keywords: Y-chromosome; Paralog; PSV; SNP; Gene conversion; Phylogeny

** Corresponding author. Tel.: +44 116 252 3427; fax: +44 116 252 3378.
Present address: Unitat de Biologia Evolutiva, Facultat de Cičncies de la Salut i de la Vida, Universitat Pompeu Fabra, Doctor Aiguader 80, 08003 Barcelona, Catalonia, Spain.

More discussion of this topic: http://archiver.rootsweb.com/th/read/GENEALOGY-DNA/2006-08/1156622088

Migration

Hyde county, North Carolina, USA

Matches

25 marker match with 29419
25 marker match with a Lyle lineage of Londonderry, N. Ireland

In comparing 25 markers, the probability that Marvin Mason and John M. Lyle shared a common ancestor within the last...
4 generations is 61.17%	8 generations is 84.92%	12 generations is 94.15%	16 generations is 97.73%	20 generations is 99.12%	24 generations is 99.66%

Contact

D. Mason -- admin@ncroots.com

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